Танец жизни. Новая наука о том, как клетка становится человеком

[42] Tobias Hirsch, Tobias Rothoeft, Norbert Teig, Johann W. Bauer, Graziella Pellegrini, Laura De Rosa, Davide Scaglione, Julia Reichelt, Alfred Klausegger, Daniela Kneisz, Oriana Romano, Alessia Secone Seconetti, Roberta Contin, Elena Enzo, Irena Jurman, Sonia Carulli, Frank Jacobsen, Thomas Luecke, Lehnhardt Marcus, Michele De Luca. Regeneration of the Entire Human Epidermis Using Transgenic Stem Cells. Nature 551 (2017): 327-332. Doi:10.1038/nature24487.

[43] Kelly Servick. A Boy with a Rare Disease Gets New Skin. Thanks to Gene-Corrected Stem Cells. Science, November 8, 2017, accessed April 5, 2019. URL: www.sciencemag.org/news/2017/ll/boy-rare-disease-gets-new-skin-thanks-gene-corrected-tem-cells.

[44] Alan Handyside, E. H. Kontogianni, K. R. M. L. Hardy, Robert Winston. Pregnancies from Biopsied Human Preimplantation Embryos Sexedby Y-Specific DNA Amplification. Nature 344(1990): 768-770. Doi:10.1038/344768a0.

[45] Darshak M. Sanghavi. Wanting Babies Like Themselves, Some Parents Choose Genetic Defects. New York Times, December 5, 2006, accessed April 5, 2019. URL: www.nytimes.com/2006/12/05/health/05essa. html.

[46] Christophe Z. Guilmoto. Sex Imbalances at Birth: Current Trends, Consequences and Policy Implications. Bangkok: United Nations Population Fund Asia, 2012. URL: www.unfpa.org/publications/ sex-imbalances-birth.

[47] Joyce Harper, L. Wilton, Joanne Traeger-Synodinos, Veerle Goossens, Celine Moutou, S. B. SenGupta, T. Pehlivan Budak, Pamela Renwick, Martine De Rycke, Joep Geraedts, Gary Harton. The ESHRE PGD Consortium: 10 Years of Data Collection. Human Reproduction Update 18 (2012): 234-247. Doi:10.1093/humupd/dmr052.

[48] Genome Editing and Human Reproduction: Social and Ethical Issues. London: Nuffield Council on Bioethics, 2018, accessed April 5,2019. URL: http://nuffieldbioethics.org/report/genome-editing-human-reproduction-social-ethical-issues/overview

.

[49] Ibid.

[50] Shiyu Luo, С. Alexander Valencia, Jinglan Zhang, Ni-Chung Lee, Jesse Slone, Baoheng Gui, Xinjian Wang, Zhuo Li, Sarah Dell, Jenice Caitlin Brown, S. M. Chen, Y.-H. Chien, W.-L. Hwu, P.-C. Fan, L.-J. Wong, P. S. Atwal, T. Huang. BiparentalInheritance of Mitochondrial DNA in Humans. Proceedings of the National Academy of Sciences 115 (2018): 13039-13044. Doi:10.1073/ pnas. 1810946115.

[51] P. A. Gammage, C. Viscomi, M.-L. Simard, A. S. H. Costa, E. Gaude, C. A. Powell, L. van Haute, B. J. McCann, P. Rebelo-Guiomar, R. Cerutti, L. Zhang, E. J. Rebar, M. Zeviani, C. Frezza, J. B. Stewart, M. Minczuk. Genome Editing in Mitochondria Corrects a Pathogenic mtDNA Mutation In Vivo. Nature Medicine 24 (2018): 1691-1695. Doi:10.1038/s41591-018-0165-9.

[52] S. R. Bacman, J. H. K. Kauppila, С. V. Pereira, N. Nissanka, M. Miranda, M. Pinto, S. L. Williams, N.-G. Larsson, J. B. Stewart, С. T. Moraes. MitoTALEN Reduces Mutant mtDNA Load and Restores tRNAAla Levels in a Mouse Model of Heteroplasmic mtDNA Mutation. Nature Medicine 24 (2018): 1696-1700. Doi:10.1038/s41591-018-0166-8.

[53] X.-H. Zhang, L. Y. Tee, X.-B. Wang, Q.-S. Huang, S.-H. Yang. Off-Target Effects in CRISPR/Cas9-Mediated Genome Engineering. Molecular Therapy-Nucleic Acids 4 (2015): e264. URL: https:// doi.org/10.1038/mtna.2015.37.

[54] Janice S. Chen, Yavuz Dagdas, Benjamin Kleinstiver, Moira M. Welch, Alexander A. Sousa, Lucas B. Harrington, Samuel Stern Berg, J. Keith Joung, Ahmet Yildiz, Jennifer A. Doudna. Enhanced Proofreading Governs CRISPR-Cas9 Targeting Accuracy. Nature 550 (2017): 407-410. Doi:10.1038/nature24268.

[55] Julie M. Crudele, Jeffrey S. Chamberlain. Cas9 Immunity Creates Challenges for CRISPR Gene Editing Therapies. Nature Communications 9 (2018): 3497.

[56] National Academies of Sciences, Engineering, and Medicine. Human Genome Editing: Science, Ethics, and Governance. Washington, DC: National Academies Press, 2017. URL: https:// doi.org/10.17226/24623.

[57] Н. Wang, Н. Yang. Gene-Edited Babies: What Went Wrong and What Could Go Wrong. PLOS Biology 17. No. 4 (2019): e3000224. URL: https://doi.org/10.1371 /joumal.pbio. 3000224.

[58] J. B. Hurlbut. Human Genome Editing: Ask Whether, Not How. Nature 565 (2019): 135. Doi: 10.1038/d41586-018-07881 -1.

[59] N. M. E. Fogarty, A. McCarthy, К. E. Snijders, В. E. Powell, N. Kubikova, P. Blakeley, R. Lea, K. Elder, S. E. Wamaitha, D. Kim, V. Maciulyte, J. Kleinjung, J. S. Kim, D. Wells, L. Vallier, A. Bertero, J. M. A. Turner, К. K. Niakan. Genome Editing Reveals a Role for OCT4 in Human Embryogenesis. Nature 550 (2017): 67—73. Doi: 10.1038/ nature24033.

[60] Maternal Mortality, World Health Organization, February 16, 2018, accessed April 5, 2019. URL: www.who.int/mediacentre/factsheets/ fs348/en/.