Песнь клетки. Медицинские исследования и новый человек

The Emperor of All Maladies: A Biography of Cancer. London: Harper Collins, 2011. О мутациях генов-драйверов и генов-пассажиров: Anderson К. et al. Genetic Variegation of Clonal Architecture and Propagating Cells in Leukaemia. Nature 469 (2011): 356-61; And or N. et al. PanCancer Analysis of the Extent and Consequences of Intratumor Heterogeneity. Nature Medicine 22 (2016): 105-13;

Vandin F. Computational Methods for Characterizing Cancer Mutational Heterogeneity. Frontiers in Genetics 8, no. 83 (2017).

2 Krivstov A. V et al. Transformation from Committed Progenitor to Leukaemia Stem Cell Initiated by MLL-AF9. Nature 442, no. 7104 (2006): 818-22.

3 Bachoo R. M. et al. Epidermal Growth Factor Receptor and Ink4a/Arf. Cancer Cell 1, no. 3 (2002): 269-77; Holland E. C. Gliomagenesis: Genetic Alterations and Mouse Models. Nature Reviews Genetics 2, no. 2 (2001): 120-9.

4 Dick J. E., Lapid от T. Biology of Normal and Acute Myeloid Leukemia Stem Cells. International Journal of Hematology 82, no. 5 (2005): 389-96.

5 Quintana E. et al. Efficient Tumor Formation by Single Human Melanoma Cells. Nature 456 (2008): 593-8.

6 Collins L, Workman P. New Approaches to Molecular Cancer Therapeutics. Nature Chemical Biology 2 (2006): 689–700.

7 Park J. J. H. et al. An Overview of Precision Oncology Basket and Umbrella Trials for Clinicians. CA Cancer J Clin 70, no. 2 (2020): ¹²5"³⁷-

8 Hyman D. M. et al. Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations. N Engl J Med 373 (2015): 726-36.

9 Kim C., Giaccone G. Lessons Learned from BATTLE-2 in the War on Cancer: The Use of Bayesian Method in Clinical Trial Design. Annals of Translational Medicine 4, no. 23 (2016): 466.

10 Rashdan S., Gerber D. E. Going into BATTLE: Umbrella and Basket Clinical Trials to Accelerate the Study of В iomarker-Based Therapies. Annals of Translational Medicine 4, no. 24 (2016): 529.

11 Yaffe M. B. The Scientific Drunk and the Lamppost: Massive Sequencing Efforts in Cancer Discovery and Treatment. Science Signaling 6, no. 269 (2013): pei3.

12 Smithers D.W, Cantab M.D. Cancer: An Attack on Cytolo-gism. Lancet 279, no. 7228 (1962): 493-9.

13 Warburg O. et al. The Metabolism of Cancer Cells. Biochemische Zeitschrift 152 (1924): 319-44.

Песни клетки

1 Stevens W. Thirteen Ways of Looking at a Blackbird, The Collected Poems of Wallace Stevens. New York: Alfred A. Knopf, 1971.

2 Ghosh A. The Nutmegs Curse: Parables for a Planet in Crisis. Chicago: University of Chicago Press, 2021.

3 McClintock B. The Significance of Responses of the Genome to Challenge. Nobel Lecture, Stockholm, December 8, 1983.

4 Schleich C. L. Those Were Good Days: Reminiscences. London: George Allen & Unwin, 1935.

Эпилог. “Лучшая версия меня”

1 Ryan К. The Test We Set Ourselves // The Best of It.

2 Shrank W. Battle Cries of Every Size. Blurb, 2021.

3 Из беседы с Полом Грингардом в феврале 2019 года.

4 Ishiguro К. Never Let Me Go. London: Faber & Faber, 2009. [Исигуро К. He отпускай меня. M.: Эксмо, 2020.]

5 Там же.

6 Там же.

7 Menand L. Something About Kathy. New Yorker, 2005.

8 Taylor D. A. et al. Building a Total Bioartificial Heart: Harnessing Nature to Overcome the Current Hurdles. Artificial Organs 42, no. 10 (2018): 970-82.

9 Sandel M.J. The Case Against Perfection. Atlantic, 2004.

10 Там же.

н Saletan W. Tinkering with Humans. New York Times, 2007.