Christen, W.G., et al., Age-related cataract in a randomized trial of vitamins E and C in men.
Arch Ophthalmol, 2010. 128(11): p. 1397–405.
В США антиоксидантные добавки составляют большую часть общего потребления:
National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey US
[2009 14 August 2020 August 27, 2020]; Available from: https://www.cdc.gov/nchs/nhanes/index.htm
В одном исследовании, в котором приняли участие почти 40 тысяч здоровых женщин в возрасте от 45 лет и старше… Другое крупное исследование не выявило пользы от добавок витамина С, Е или бета-каротина:
Mursu, J., et al., Dietary supplements and mortality rate in older women: the Iowa Women’s Health Study.
Arch Intern Med, 2011. 171(18): p. 1625–1633.Song, Y., et al., Effects of vitamins C and E and beta-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trial.
Am J Clin Nutr, 2009. 90(2): p. 429–37.Lee, I.M., et al., Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women’s Health Study: a randomized controlled trial.
JAMA, 2005. 294(1): p. 56–65.Cook, N.R., et al., A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of cardiovascular events in women: results from the Women’s Antioxidant Cardiovascular Study.
Arch Intern Med, 2007. 167(15): p. 1610–8.
Исследование The Physicians’ Health Study II, в котором приняли участие более 14 тысяч мужчин-врачей в возрасте от 50 лет и старше, показало, что ни витамин Е, ни витамин С не снижают риск сердечных заболеваний, инсульта, диабета, рака или катаракты:
Gaziano, J.M., et al., Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians’ Health Study II randomized controlled trial.
JAMA, 2009. 301(1): p. 52–62.Sesso, H.D., et al., Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians’ Health Study II randomized controlled trial.
JAMA, 2008. 300(18): p. 2123–33.Sesso, H.D., et al., Multivitamins in the Prevention of Cardiovascular Disease in Men: The Physicians’ Health Study II Randomized Controlled Trial.
JAMA, 2012. 308(17): p. 1751–1760.
…добавки селена и витамина Е по отдельности или вместе, но рак предстательной железы предотвратить не удалось:
Lippman, S.M., et al., Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
JAMA, 2009. 301(1): p. 39–51.Klein, E.A., et al., Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
JAMA, 2011. 306(14): p. 1549–56.