Источник молодости. Как продлить жизнь с помощью еды, секса и смеха. Выводы из масштабного исследования старения

Martinsen, E.W., Physical activity in the prevention and treatment of anxiety and depression. Nord J Psychiatry, 2008. 62 Suppl 47: p. 25–9.

…выяснили, что уровень спортивной нагрузки значительно ниже среди взрослых, страдающих депрессией:

Lуpez-Torres Hidalgo, J., et al., Effectiveness of physical exercise in the treatment of depression in older adults as an alternative to antidepressant drugs in primary care. BMC Psychiatry, 19, 21 (2019).

Hamer, M., K.L. Lavoie, and S.L. Bacon, Taking up physical activity in later life and healthy ageing: the English longitudinal study of ageing. Br J Sports Med, 2014. 48(3): p. 239–43.

Mammen, G. and G. Faulkner, Physical activity and the prevention of depres- sion: a systematic review of prospective studies. Am J Prev Med, 2013. 45(5): p. 649–57.

Donoghue, O., M. O’Connell, and R.A. Kenny, Walking to wellbeing: phy- sical activity, social participation and psychological health in Irish adults aged 50 years and older. Dublin: The Irish longitudinal study on ageing (TILDA), 2016.

Teychenne, M., K. Ball, and J. Salmon, Physical activity and likelihood of depression in adults

Примечательно, что упражнения увеличивают размер гиппокампа… Увеличивается гиппокамп – усиливается и высвобождение белка BDNF:

Hillman, C.H., K.I. Erickson, and A.F. Kramer, Be smart, exercise your heart: exercise effects on brain and cognition.Nat Rev Neurosci, 2008. 9

(1): p. 58–65.

van Praag, H., et al., Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci, 2005. 25(38): p. 8680–5.

Cotman, C.W. and N.C. Berchtold, Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci, 2002. 25(6): p. 295–301.

Creer, D.J., et al., Running enhances spatial pattern separation in mice. Proc Natl Acad Sci USA, 2010. 107(5): p. 2367–72.

Vaynman, S., Z. Ying, and F. Gomez-Pinilla, Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur J Neurosci, 2004. 20(10): p. 2580–90.

Li, Y., et al., TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron, 2008. 59(3): p. 399–412.

…аэробные упражнения увеличивают количество клеток в других областях мозга, участвующих в основных когнитивных функциях:

Colcombe, S.J., et al., Aerobic exercise training increases brain volume in aging humans. J Gerontol A Biol Sci Med Sci, 2006. 61

(11): p. 1166–70.

Colcombe, S.J., et al., Cardiovascular fitness, cortical plasticity, and aging. Proc Natl Acad Sci U S A, 2004. 101(9): p. 3316–21.

Rosano, C., et al., Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment. J Gerontol A Biol Sci Med Sci, 2010. 65(6): p. 639–647.

Erickson, K.I., et al., Physical activity predicts gray matter volume in late adulthood: the Cardiovascular Health Study. Neurology, 2010. 75(16): p. 1415- 22.

Erickson, K.I., et al., Aerobic fitness is associated with hippocampal volume in elderly humans. Hippocampus, 2009. 19(10): p. 1030–9.